Clévio Nóbrega

I am interested in the study of the molecular and cellular mechanisms underpinning the pathogenesis of different brain disorders, with a particular focus in Polyglutamine disorders. A better understanding of these mechanisms is a key point to the development of new therapeutic strategies based on advanced systems as gene or cell therapies. In my research I combine the use of in vitro systems, with the analysis of biological samples for patients and the development of in vivo models based in the expression of lentiviral vectors.